Mixture toxicity of engineered nanomaterials and co-existing environmental pollutants

Göteborgs Universitet

Department of Biological and Environmental Science

Natur Medicin

The Master project will carried out within a larger, international research project (MENACE) funded by the Swedish Research Council Formas. The MENACE project aims to go beyond classical nano-ecotoxicological studies taking into consideration nanoparticle interactions with traditional, i.e. chemical pollutants that may co-exist in the environment and/or in the body. Since this issue remains hitherto almost completely unaddressed, the degree project bears a great potential to generate new scientific knowledge and contribute to advancing the development of this novel and exciting research area.

The objective of the Master project will be to find out if, how and to which extent mixtures of engineered nanomaterials and organic chemical pollutants may cause toxicity in fish. The project will focus on determining toxicokinetic and toxicodynamic interactions at the molecular and cellular level by means of the use of conventional and advanced in vitro models based on fish cell cultures. The experimental work will include the characterisation/further development of the test systems, exposure of the cell cultures to engineered nanomaterials and nanomaterial-chemical mixtures under different experimental conditions, and measurement of various biomarker responses using enzyme activity assays and gene expression analysis, amongst others.

Project start

September 2017

Interested? / Deadline for application

If you are interested and would like to have further information on the project and/or would like to  apply for the position please reply to this advert until until 30 June 2017.

Supervision and work place

Work place will be the Zoological Institute (Medicinaregatan 18A), Department of Biological and Environmental Sciences, University of Gothenburg.

Requirements

Ideal applicants are MSc level students with a strong background and/or interest in Environmental-, Nano- an In vitro Toxicology and a high motivation to conduct scientific research. Previous experience in research, in particular in cell culture, biochemistry and molecular biology techniques is highly appreciated, but not a prerequisite. In addition, she/he should have good organizational and analytical skills, a positive and proactive attitude, and be able to work both independently and in a team. Furthermore, since we are an international research group, the applicant needs to have a high level of English in speaking, reading and writing.


Sista ansökningsdag
2017-06-30
Kontakt
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